(Rather, I understand, like what's happened to Lost.)
The Simone story is...meh...and I sometimes skip past the Jessica/Niki bits -- I'm just not taken by that story yet.
I like Hiro a lot -- his enthusiasm is definitely endearing (and all the Star Trek references don't hurt :-)), and his excitedly showing Niki's kid the comic book that's about him was just awesome, and Mohinder's accent is...well, melt-worthy -- yay for the intro and epilogue he does on all the episodes. I sense nothing but bad happening with the whole Claire and her father thing.
By the way -- it seems a huge stretch that Hiro's friend (Ando?) watched Niki on-line, so I imagine that'll have some meaning later, but we'll see...it's just that years of watching Babylon 5 and other arc-driven shows have given me something of a sixth sense for things that are too convenient.
Also? Niki's (ex-?) husband reminds me of Gunn on Angel...a lot.